Further analysis across four AML subtypes (C1-C4) revealed that C2 contained IGF2BP3, RBM15, HNRNPC, IGF2BP2, METTL14, RBM15B, and IGF2BP1; C3 contained YTHDF2, FMR1, CBLL1, YTHDC2, YTHDC1, and YTHDF1; C1 contained HNRNPA2B1, WTAP, YTHDF3, FTO, METTL3, and LRPPRC; and C4 contained VIRMA and ALKBH5. This evidence concerns the gene METTL3 and acute myeloid leukemia.