Additionally, FTO can enhance the stability of MYC and CEBPA mRNA, thereby promoting cell proliferation [11], and METTL14 and YTHDF2 promote the self-renewal of leukaemia stem cells (LSCs)/leukaemia initiating cells (LICs), while ALKBH5K promotes LSC proliferation and induces apoptosis [10, 12, 13]. The gene discussed is YTHDF2; the disease is leukemia.