To explore the mechanisms underlying erythrocyte-YTHDF2 + cell communication in AML, CellChat was used to examine the interaction between YTHDF2 expression in Erythrocytes and other cells (Fig. 4j and k), and it was observed that the YTHDF2 high-expression group displayed significant interactions with specific genes (Fig. 4l). The gene discussed is YTHDF2; the disease is acute myeloid leukemia.