S100A8 and infection: In contrast to the cagA mutant, the animals infected with the cagA restorant strain showed evidence of dysplasia or adenocarcinoma in proportions that were similar to the WT strain: 40% with dysplasia at 2 months post-infection and 60% of gerbils with dysplasia or adenocarcinoma at the 3 month timepoint (Fig. 6A).