CEACAM5 and cancer: Although malignant neoplasms tend to have higher CEA levels, no direct and conclusive correlation between CEA levels and the presence of malignancy has been reported in the literature.9,24 However, because of the wide range of sensitivity and specificity of chemical analyses, it is difficult to make an interpretation.7,25 The sensitivity of CEA was 63% with a specificity of 93% in differentiating between IPMNs and MCNs.26 Different cutoff values for CEA were evaluated in the studies.