CEACAM5 and cystic neoplasm: This is because while amylase can differentiate PCs from nonmucinous cysts, it lacks the ability to differentiate between mucinous cysts and nonmucinous cysts.31 The European Study Group on Cystic Tumours of the Pancreas23 reported a combined analysis of CEA, lipase levels, and cytology in cyst fluid related to better accuracy rates for differentiating mucinous from nonmucinous PCNs.