In the pH3 fraction, 27 unique proteins were identified, including PRG4, SERPINC1, ITIH2, APOC2, and F12, which aligned with the upregulation of the corresponding genes in PCa patients reported in TCGA data; notably, ITIH2 and F12 were also identified in the data analysis for combined fractions. This evidence concerns the gene ITIH2 and posterior cortical atrophy.