Numerous malignancies have been linked to SNHG3 as an oncogene.8,28,29 For instance, Dai et al found that SNHG3 accelerated the development of bladder cancer,28 and Xie et al suggested that SNHG3 accelerated the metastasis of gastric cancer.29 In this study, CCA tissues and cells had elevated levels of SNHG3. This evidence concerns the gene SNHG3 and cholangiocarcinoma.