The contractile protein known as MYH9, which is classified as non-muscle myosin IIA, functions as an actin-binding protein, has a significant impact on promoting tumor development, and is strongly associated with a negative outcome for patients suffering from CRC.36 In the present investigation, to explore the effector molecules of miR-542-3p, an exploration of the starBase database revealed that MYH9 is a gene targeted by miR-542-3p. The gene discussed is MYH9; the disease is colorectal carcinoma.