ERBB2 and neoplasm: In these cases, HER2 status serves as an important prognostic marker, correlating positively with tumor size, invasiveness, and lymph node metastasis (Gravalos and Jimeno, 2008; Swain et al., 2023; Ivanova et al., 2022; Guan et al., 2023; Luo et al., 2018).