Their study demonstrated that SLC26A4-AS1 mediates tumor metastasis by regulating DDX5.10 Yi et al. reported diminished SLC26A4-AS1 levels, closely linked to prognosis, survival, and immune infiltration in patients with breast cancer.11 Through RT-qPCR detection, we observed that SLC26A4-AS1 also showed low levels in plasma and cell samples of rectal cancer compared with healthy controls, which was consistent with the above conclusions. This evidence concerns the gene DDX5 and neoplasm.