SLC26A4 and rectal cancer: Furthermore, establishing ROC curves aided in elucidating the potential clinical diagnostic value of lncRNA.18 In earlier discussions on colorectal cancer, ROC analysis confirmed the ability of SNHG11 to distinguish early-stage patients.19 Similarly, our study concluded that SLC26A4-AS1 had an AUC of 0.937 in the identification of rectal cancer patients with high sensitivity and specificity in diagnosing rectal cancer, thereby holding promise as a diagnostic factor.