PCSK1N and rectal cancer: Literature suggests that elevated Ktrans values accompany the deterioration of rectal cancer, while increased Kep content is associated with angiogenesis in rectal cancer.22 Li et al. also underscored the diagnostic efficacy of MRI blood perfusion parameters for patients with rectal cancer.23 Therefore, the association of SLC26A4-AS1 with Ktrans and Kep values further elucidated the predictive and pathological staging potential of SLC26A4-AS1 in rectal cancer.