The model demonstrated good performance in 5-year survival prediction.42 A recent study identified 6 cell subpopulations and revealed 11 prognosis-related DEGs associated with HCC prognosis.33 Another study analyzed cytotoxic CD8+ T cell subsets and found that one of the subsets was closely related to the prognosis and survival of HCC. The gene discussed is CD8A; the disease is hepatocellular carcinoma.