MiR-3619-5p plays a crucial role in inhibiting cell proliferation and increasing drug sensitivity in cisplatin-resistant cutaneous squamous cell carcinoma (CSCC) cells by targeting and suppressing the expression of karyopherin subunit alpha 4 (importin alpha 3, KPNA4), which is responsible for the nuclear translocation of many transcription factors [75]. This evidence concerns the gene KPNA4 and cutaneous squamous cell carcinoma.