Regarding gynecological observation, a statistically significant association (P<0.05) of CMVs with history of miscarriage was observed on screening for both anti-CMV IgG and IgM antibodies 8 (5.4%) versus 2 (1.3%) by ELISA, respectively, while a statistically non-significant (p>0.05) association were observed in the distribution of anti-CMV IgG, IgM, both IgG and IgM Abs among gestational age, as revealed in Table 2. This evidence concerns the gene CD40LG and spontaneous abortion.