However, in the group of BoDV-1 negative MDD patients, participants showed an increased variability of IL-8 concentrations with values ranging from 4.99 to 21.20 pg/ml, showing a concomitant high variability in mean relative fronto-central EEG alpha power with values of up to 6% (Figure 3 and Table 1). Here, CXCL8 is linked to major depressive disorder.