CXCL8 and acute respiratory distress syndrome: Observational studies have increasingly highlighted a significant association between ARDS and various interleukins, such as Interleukin-8 (IL-8), Interleukin-2 (IL-2), Interleukin-6 (IL-6), and Interleukin-1β (IL-1β) (Wang et al., 2019).