Moreover, increased blood BD‐tau concentrations were associated with unfavorable outcomes after traumatic brain injury [30] and ischemic stroke [29, 31], outperforming other brain injury markers such as neurofilament light (NfL) and glial acidic fibrillar protein (GFAP) at tracking CNS insults [30, 31, 32]. This evidence concerns the gene NEFL and ischemic stroke.