Expression and localization of IL-8, CXCR1, and CXCR2 in normal tissues (Fig. 1 a-b) and HNSCC tumors (Fig. 1 c-h) were evaluated with a commercially available tissue array containing 70 tumor cases of unknown HPV status and 10 normal tissues. This evidence concerns the gene CXCR1 and head and neck squamous cell carcinoma.