CXCL8 and neoplasm: The study reported significantly higher levels of IL-8 mRNA in tumor tissues compared with healthy mucosa but had no information on HPV status, and showed that patients with high IL-8 mRNA levels had a 5-year local recurrence-free survival of 65.5% compared to 90.2% for those with low IL-8 mRNA in the tumor pre-treatment [34].