In a post-hoc analysis of microalbuminuria during follow-up, GLP1-RA users has significantly lower levels compared with DPP4i users; however, this analysis is limited by a large proportion of data missingness (Supplementary Table S1).The pattern of association of GLP1-RA with decreased acute healthcare utilization, CKD progression and all-cause death despite no difference in CV outcomes persisted in additional analyses excluding patients with ESRD (Supplementary Table S2) and after adjusting for A1c at follow-up and use of other anti-hyperglycemic medications (Supplementary Table S3). This evidence concerns the gene GCG and chronic kidney disease.