EGFR and non-small cell lung carcinoma: To further investigate the role of neutrophils infiltration in mediating response or resistance to EGFR-TKIs, we conducted scRNA sequencing on 34 samples (22 pretreatment and 12 resistant) from 22 EGFR-mutant NSCLC patients received third-generation EGFR-TKIs in a real-world cohort.