KDM1A and esophageal squamous cell carcinoma: Specifically, Kaplan-Meier curves demonstrated that the 5-year OS rate of ESCC patients with high expression of KDM1A at early stages, defined as localized (Fig. 1D, left, 65% vs. 90%, p = 0.0077), LNM negative (Fig. 1E, left, 60% vs. 90%, p = 0.0056), LN number<2 (Fig. 1F, left, 60% vs. 80%, p = 0.0114), was significantly lower than that of patients with low expression of KDM1A.