NR4A3 and cervical cancer: However, several DMRs near the NR4A3 promoter were unmethylated on the integrated allele, including an 821 bp DMR in exon two of NR4A3 at the 3′ end of an unmethylated promoter element (Fig. 6G, bottom), distinguishing it from other cervical cancer samples we profiled (Supplemental Fig. S17, bottom).