As glucanemia in lupus models were reported caused by either gut permeability defect or increased abundance of fungi in the gut [7–12, 19], gut mycobiota (from feces and different sections of the intestine) during SLE progression in SLE-prone mice were investigated in pristane and FcgRIIb-/- models, and age-matched healthy mice at 2–10 months old (from pre-clinical SLE to established full-blown SLE lupus conditions). Here, FCGR2B is linked to systemic lupus erythematosus.