For example, the tumor suppressors BRCA2 and RAD51 paralog complex BCDX2 promote RAD51-ssDNA filament formation and stability while several DNA helicases and translocases such as RAD54, the RecQ family, HELQ, RTEL1, and FBH1 can disassemble RAD51-ssDNA or -dsDNA filaments(5, 11–16). Here, RAD51 is linked to neoplasm.