MKI67 and neoplasm: Similarly, in our study, moderate negative correlations were identified between RTE and Ki-67 mean in the hepatobiliary phase (r = −0.50, p = 0.01) and Ki-67 max (r = −0.55, p < 0.01) in the CRCLM group, suggesting that lower RTE could indicate higher proliferative activity and more aggressive tumor behavior.