Of the malignant renal tumors, 48 patients (mean age 55.9 ± 11.6 years) were diagnosed with ccRCC (World Health Organization/International Society of Urological Pathology: grade I, n = 10; grade II, n = 24; grade III, n = 10; grade IV, n = 4) while 22 patients (mean age 52.4 ± 14.7 years) had non-ccRCC, including papillary RCC (n = 4), chromophobe RCC (n = 12), unclassified RCC (n = 2), MiT family translocation RCC (n = 1), TFE3 translocation RCC (n = 1), TFE3 gene fusion-related RCC (n = 1), and Xp11.2 translocation/TFE3 gene fusion-related RCC (n = 1). This evidence concerns the gene TFE3 and cancer.