These risk factors included age, fever, cough, skin lesions, POAL, hepatomegaly, splenomegaly, oral candidiasis, bacterial pneumonia, Hb, WBC, PLT, elevated ALT, elevated AST, AARI, and CD4+ T cell count (P < 0.1) (Table 3). The gene discussed is GSTM1; the disease is oral candidiasis.