A 50-year-old male with T2DM, HTN, hyperlipidemia, legal blindness, and deafness presented with constipation, oliguria, and dark-colored urine.The patient was on Atorvastatin 20 mg (QD), Metformin 500 mg (QD), Lisinopril 5 mg (QD) with positive past myotoxic DH. Lab results revealed a peak CK of 359,910, AST/ALT of 2222/432, LDH of >6,000, and creatinine of 3.51 with positive blood test in U/A. The patient survived. The gene discussed is GPT; the disease is hypertensive disorder.