A 57-year-old patient with a history of obesity class 2, HTN, and HLP presented with fever, malaise, and myalgia. The patient was on Hydralazine 50 (BID), Furosemide 40 (QD), and Rosuvastatin 5 (QD) with positive past myotoxic DH. Lab results showed a peak CK of 1,083,744, AST/ALT of 3995/751, and creatinine of 7.6 with positive blood test in U/A. The patient expired. The gene discussed is GPT; the disease is hypertensive disorder.