A 78-year-old male with T2DM and HTN presented with asthenia, fever, severe myalgia, muscle weakness, and dark-colored urine. Lab results revealed a peak CK of 22,511, AST/ALT of 972, and creatinine of 3.2 with positive blood test in U/A. The patient survived. The gene discussed is GPT; the disease is type 2 diabetes mellitus.