Interestingly, FGFR family members are expressed not only on microglia but also on a number of immune cells, suggesting their broad contribution to immunity and inflammation: FGFR2 mediates chemotaxis in neutrophils (38), and FGFR1 is expressed in T-cells (39, 40) as well as on macrophages and lymphocytes in lupus nephritis (41). This evidence concerns the gene FGFR1 and lupus nephritis.