In the multivariate analysis, the independent prognostic factors were age (hazard ratio [HR]: 1.03; 95% confidence interval [CI]: 1.02–1.03), KPS (HR: 0.98; CI: 0.97–0.99), BMI (HR: 0.76; CI: 0.60–0.96), diabetes (HR: 1.47; CI: 1.11–1.94), targeted therapy (HR: 0.80; CI: 0.64–1.00), Hb (HR: 0.98; CI: 0.98–0.99), WBC (HR: 1.06; CI: 1.02–1.09), LDH (HR: 1.00; CI: 1.00–1.00), CRP (HR: 1.00; CI: 1.00–1.01), PLR (HR: 1.00; CI: 1.00–1.00), and LMR (HR: 0.91; CI: 0.83–0.99). The gene discussed is GSTM1; the disease is diabetes mellitus.