The network includes genes such as IL6, IL1B, COL1A1, COL5A1, IL10, IFNG, PRL, MPO, ACE, CCL2, REN, and F2, which are linked to a wide array of diseases, including inflammatory bowel disease, diabetes mellitus, rheumatoid arthritis, and Parkinson’s disease. This evidence concerns the gene REN and rheumatoid arthritis.