By analyzing the top 5 transcription factors from the subpopulation of neurons in RE-CI, we observed an increase in the expression of transcription factor Sox11, which regulated the gene Dcx associated with cognitive impairment in the InN1 subpopulation, as well as the gene Lrp1b related to cognitive impairment in the ExN1 and ExN3 subpopulations (Figure 7B). This evidence concerns the gene DCX and Cognitive impairment.