We used relevant existing guidelines for AIS and AMI where necessary and proposed the following treatment algorithm presented in Figure 2, considering the window of presentation and management possibilities based on the nature of stroke (large-vessel occlusion or not) and nature of MI (STEMI or NSTEMI). Time being the major limiting factor in questions of reperfusion with tissue plasminogen activator, it is crucial that these patients are managed using the appropriate intervention as quickly as possible to minimise tissue loss and maximise chances of recovery and reduce morbidity. Here, PLAT is linked to Stroke.