Furthermore, Ad can reduce the volume of adenoid hypertrophy, lower the bacterial load, reduce proliferation of T and B lymphocytes, and reduce level of inflammatory factors.15,16,18 As shown by Nguyen LH et al.,19 TTI+Ad can effectively reduce IL-6 and IL-8 levels in patients, while Ad significantly inhibits generation of inflammatory factors, alleviating the inflammatory response of children, and accelerating the recovery. Here, IL6 is linked to hyperostosis.