In Hodgkin’s lymphoma cells, LT4, CAM29, and MN8 act to reduce the release of ADAM10 substrates (CD30 and TNF-α), lower the ATP content of lymphoma cells, and increase the release of lactate dehydrogenase, ultimately inhibiting the growth and proliferation of lymphoma cells (Pece et al., 2022). Here, TNFRSF8 is linked to Hodgkins lymphoma.