After intervention, the insulin usage rate in the GDM Intervention Group was (1/120) 0.83%, while the insulin usage rate in the GDM Control Group was (5/120) 4.66%, with a statistically significant difference, which means that the one-day outpatient and late intervention measures for diabetes, including regular exercise, regular follow-up visits and personalized question answering, can effectively control the blood glucose level of GDM and reduce the insulin use rate. This evidence concerns the gene INS and diabetes mellitus.