In GDM Intervention Group, HOMA-IR was positively correlated with weight gain, E, NE and cortisol after intervention (r = 0.161, 0.806, 0.428, 0.506; p < 0.05, <0.01, <0.01, <0.01), and negatively correlated with SOD (r = −0.213, p < 0.01). This evidence concerns the gene SOD1 and gestational diabetes.