For instance, miR-16, miR-150, and miR-423 indirectly stimulate the NF-κB pathway by specifically targeting lactate dehydrogenase-A (LDH-A), forkhead box protein O4 (FOXO4), and TNFAIP3-interacting protein 2 (TNIP2), consequently facilitating cancer advancement (188–190). The gene discussed is TNIP2; the disease is cancer.