AKT1 and neoplasm: Furthermore, miR-92b also targets disabled homolog 2 interacting protein (Dab2IP), while miR-146 targets tumor necrosis factor receptor-associated factor 6 (TRAF6) and tripartite motif-containing protein 2 (TRIM2), thereby weakening the suppressive effect of the PI3K/AKT signaling pathway and promoting tumor progression.