For poorly differentiated carcinomas with no clear gland formation, markers of squamous differentiation (p63, p40, CK5/6), neuroendocrine markers (synaptophysin, chromogranin), urothelial markers (GATA3, p63), and renal markers (PAX8) may be indicated based on the available clinical history and morphology of the tumor (39). The gene discussed is KRT5; the disease is carcinoma.