Additionally, high-intensity interval training (HIIT) has been shown to be feasible and more time-efficient than moderate-intensity training, while also being superior in improving VO2peak, body composition, mitochondrial functioning, insulin sensitivity, and glycemic control in patients with T1D and T2D (Kanaley et al., 2022; Murillo et al., 2022). The gene discussed is INS; the disease is type 1 diabetes mellitus.