Recent studies have shown that antioxidant selenium (Se), Eicosapentaenoic acid (EPA), and silver nanoparticles (AgNPs) can induce apoptosis by stimulating TRPM2 channel activity, thereby increasing the anticancer effect of chemotherapeutic drugs cisplatin (CiSP) and docetaxel on GBM [98–100]. Here, TRPM2 is linked to glioblastoma.