DYRK1A and Anxiety: A protein-truncating mutation in the DYRK1A gene (Ile48LysfsX2) was reported in a human autistic individual with the following symptoms: 1) microcephaly, 2) intellectual disability, 3) anxiety, 4) ASD-related social deficits, 5) impaired speech, 6) stereotypic behavior, and 7) febrile seizures [6, 10].