rs189139822, located in an intron of WNK3, was identified in the r-XCI (MAF = 9.70 × 10−3, OR = 1.481 [1.263–1.735], P = 1.29 × 10−6) and e-XCI (MAF = 9.10 × 10−3, OR = 1.343 [1.192–1.513], P = 1.20 × 10−6, Supplementary Table S8) meta-analyses excluding AD-proxy cases (Table 1 and Supplementary Fig. S8). This evidence concerns the gene WNK3 and Alzheimer disease.