For the risk of periodontitis in patients with diabetes, age, race, education level, moderate leisure, high work intensity, income-to-poverty ratio, alcohol consumption frequency, smoking status, and the levels of ALB, ALT, TC, Cr LDH, TP, K, Osm, and glycohemoglobin (GHb%) were predicted by a comprehensive assessment of 17 risk predictors. This evidence concerns the gene ALB and diabetes mellitus.