After exposure to RNase R treatment, we measured the mRNA levels of circSMOC1 and linear SMOC1 in NSCLC cells and found that circSOMOC1 exerted a resistance to RNase R treatment as compared with linear SMOC1 in PC9 and 95D cells (Figure 1G). The gene discussed is SMOC1; the disease is non-small cell lung carcinoma.