RBBP9 and infectious otitis media: We identified 4 overlapping signatures that were significantly upregulated in Rbbp9-/- mice: “interferon_gamma_response,” “interferon_alpha_response,” “oxidative_phosphorylation,” and “adipogenesis.” In addition, we observed a clear increase in pSTAT1 expression in AOM/DSS-induced tumors in Rbbp9-/- mice (Figure 6E and F).