PECAM1 and diabetes mellitus: Diabetes mellitus caused gain of time-dependent fibrogenic kidney phenotypes, a higher rate of EMT, as evidenced by higher vimentin expression in E-cadherin–positive cells, and a higher rate of EndMT, as shown by higher αSMA in CD31-positive cells, at 24 weeks after STZ injection, when compared to nondiabetic control mice (Fig. 1, A and B).