In the recessive model, the genotypic combination of ACE2-wild (GG) with GSTT1-null (OR=3.57, CI=1.06-16.24, P=0.05) or present (OR=9.30, CI=2.45-46.34, P=0.00) demonstrated an association with the development of T2DM (Table 5). This evidence concerns the gene ACE2 and type 2 diabetes mellitus.