Blood tests showed worsening of anemia [Hb from 9.1g/dL (baseline) to 4.8g/dL], a drop in reticulocyte absolute number [from 255 × 109/L (baseline) to 80 × 109/L], 65 orthochromatic erythroblasts per 100 WBCs, an increased lactate dehydrogenase level [from 566 U/L (baseline) to >6.000 U/L], and an increased indirect bilirubin level [from 1.6 mg/dL (baseline) to 2.7mg/dL]. This evidence concerns the gene GSTM1 and anemia (phenotype).