RAB27A and neoplasm: The feasibility of using exosomes as diagnostic markers or prognostic biomarkers has been demonstrated by a growing body of evidence.[32] Moreover, exosomes can serve as drug delivery systems to deliver gene therapy, chemotherapy drugs, and so on.[33] Numerous articles indicate that inhibiting exosome secretion through gene editing of exosome‐related genes, such as ras‐related protein rab‐27A (Rab27a) or using GW4869, can effectively restrain tumor progression and enhance the efficacy of immunotherapy;[34] yet, there remains a need for considering the safety of these approaches for the host.