Innate immune cells recognize A. baumannii and initiate the production of pro‐inflammatory cytokines and chemokines, which largely determine the fate of the infection.[6] Macrophages, the main immune cell population of the alveolar airspace, are endowed with cytosolic and membrane receptors, and are critical for anti‐infective immune response upon many respiratory bacterial infection.[21] Therefore, we further evaluated the role of the cGAS‐STING pathway in CRAB‐infected macrophages. This evidence concerns the gene CGAS and infection.