ATAD1 and amyotrophic lateral sclerosis: In particular, variants in VCP cause a specific type of FTLD, inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia (IBMPFD) and amyotrophic lateral sclerosis (ALS), also referred to as multisystem proteinopathy type 1 (MSP1) (Watts et al., 2004; Pfeffer et al., 2022; Scarian et al., 2022).