In 2020 Morlino et al. [36] coined the term COL1 overlap disorder pertaining to individuals with previously reported OIEDS1 and OIEDS2 due to combined symptoms of osteogenesis imperfecta type 1 (non-deforming OI with blue sclerae) and Ehlers Danlos syndromes due to structural COL1A1 and COL1A2 variants without fulfilling the clinical criteria for these conditions. Here, COL1A2 is linked to osteogenesis imperfecta.