The results of the univariate Cox regression analysis indicated that age, atrial fibrillation, hs-CRP, serum albumin, CAR, serum creatinine, eGFR, hemoglobin, lactate dehydrogenase (LDH), log-transformed NT-pro BNP, LVEDD, LVESD, LVEDV, and LVESV were significantly associated with the risk of MACE. This evidence concerns the gene NPPB and atrial fibrillation.